This research focuses on the biodiversity and the evolutionary history of the world-wide medicinal plant genus, Dracaena, and the plant genus Pleomele in Hawaii. The debate concerning the relationship between Dracaena and Pleomele has continued to today where some authors continue to include Pleomele within Dracaena. Clear phylogenetic evidence to separate Pleomele has been lacking. Phylogenetic relationship among the 43 taxa within the Dracaena and Pleomele were reconstructed. DNA sequences from the chloroplast DNA intergenic spacer, trnL-trnF, and was analyzed.